Sentence examples for mouse models they from inspiring English sources

In mouse models, they reduce angiogenesis and suppress metastasis.

Many of them have found satisfying careers applying their scientific knowledge and training on the production side of things, servicing scientists around the world with the mouse models they need to investigate cancers, developmental diseases such as Down syndrome, aging-related diseases like Alzheimer's, and the ever widening range of mouse models that serve as proxies for human ailments.

While no significant increase of REST RNA levels was found in HD cellular and mouse models, they demonstrated that loss of Htt function leads to nuclear translocation of REST in various HD cellular models, thereby causing a REST-mediated repression of several neuronal genes and contributing to neuronal dysfunction.

If some features can be found that persist across mouse models, they may ultimately demonstrate applicability to human disease.

Furthermore, because they naturally develop spontaneous cancers, in contrast to mouse models, they constitute an excellent comparative model for cancer [ 27].

Using deletion-reintroduction mouse models, they found that reintroduction of miR-19a/b rescued oncogenicity but not to the same extent as reintroduction of the entire cluster, indicating the pro-tumourigenic activity within this cluster.

Monocytes are recruited early in atherosclerotic plaque development where, through the action of MCSF (and possibly IL-4, as evident in the mouse model), they differentiate into macrophages (Mϕ), primarily skewed towards an M2 form.

As a mouse model they used xenotransplants with a luciferase-expressing, Merlin-deficient meningioma cell line Ben-Men-1.

Using a different mouse model they proved that miRNA treatment did not induce nonspecific immune responses in mice by measuring serum cytokines.

In a transgenic mouse model, they detected insulinomas of less than 1 mm in diameter using [Lys(In-DTPA)]exendin-4 as tracer.

Here, the authors show that, although cochlear hair cells are specified normally in a WHS mouse model, they are disorganised and display sterocilia defects.