Sentence examples for mouse models supports from inspiring English sources
Emerging evidence from human patients and mouse models supports that allelic heterogeneity contributes to phenotypic variability.
Familial clustering and mouse models support the presence of monogenic causes.
In this review, we will discuss the molecular evidence and mouse models supporting specific 5q candidates as tumor suppressors of (del)5 or 5q– MDS and their roles in growth control.
Our results using preclinical mouse models support the NF-κB pathway as a potential therapeutic target for a defined subset of lung adenocarcinoma.Using small-molecule compounds that inhibit NF-κB activity, we provide evidence that NF-κB inhibition has therapeutic efficacy in the treatment of lung cancer.
The data from FHM mouse models support the view of migraine as a disorder of brain excitability characterized by dysregulation of the excitatory-inhibitory E/I balance, and point to episodic disruption of the E/I balance and neuronal hyperactivity due to excessive recurrent glutammatergic transmission as the basis for vulnerability to CSD ignition in FHM.
Studies in mouse models support Dax1 as having both pro-testis [34], [35] and anti-testis functions [33].
Evaluation of the features of RTT suggests that the basis of this disease could be an alteration of neuronal plasticity and studies of RTT mouse models support this suggestion.
These consistent findings in two different mouse models support the critical role of NADPH oxidase in down-regulating inflammation as opposed to an individual phox protein functioning independently of NADPH oxidase or an artifact introduced during generation of one of the knockout colonies.
In vivo and in vitro model systems including transgenic mouse models support a relationship between erbB2 alterations and mammary tumorigenesis.
Separate lines of evidence from transgenic mouse models support the specific functional importance of myelin sulfatide content in the CNS.
Just like in the human brain, studies using AD mouse models support the pathogenic role of oligomers.
