Sentence examples for mouse models strengthens from inspiring English sources
Our observation that TRIM62 is persistently increased in muscles of critically ill patients at high risk of developing ICUAW and in all atrophy mouse models strengthens this hypothesis.
Our finding of impaired HRV and circadian rhythmicity in tg MSA mice associated with degeneration of the nucleus ambiguus suggests that a cardinal non-motor feature of human MSA can be reproduced in the mouse model strengthening its role as a valuable testbed for studying selective vulnerability and assessing translational therapies.
Recent genetic mouse models have strengthened this association.
APP overexpression has been employed in fly models of AD [25], [26]; moreover, altered circadian patterns of activity have been reported in the APP23 mouse model, further strengthening this possibility [27].
The concept of targeted reactivation of wtp53 for therapy is greatly strengthened by mouse models, where genetic restoration of p53 in established tumors leads to clinical tumor regression.
The confirmation of such early synaptic change in different mouse models of raised amyloid-β greatly strengthens the significance of these studies and is in agreement with the suggestion that in Alzheimer's disease, synaptic derailment is likely to occur long before symptom onset and these studies would suggest, also prior to plaque deposition.
One test of this hypothesis is to determine whether light therapy designed to strengthen this intrinsic timing system can delay the disease progression in mouse models.
The validity of our hypothesis that p53 activation may result in premature neuronal differentiation, is further strengthened by the analysis of the expression of RR genes in mouse models of neurological disorders.
A comprehensive approach that considers clinically relevant mouse models with both an integrated biomarker strategy and a complementary modeling and simulation effort will strengthen the current oncology drug development paradigm.
There are now mouse models of Parkinson's.
The problem is there are no appropriate mouse models that can mimic the human situation.
