Sentence examples for mouse models so from inspiring English sources

Vaccination studies via laserporated skin have been performed only in mouse models so far.

Mouse models so far have not gained substantial clinical benefit, because the architecture of mouse skin significantly differs from human skin.

Previous studies demonstrated that systemic administration of MIP-1α can significantly exacerbate colitis in mouse models, so that decrease in levels of MIP-1α, as observed in TNF-α NiMOS groups, suggests an improvement of the disease.

If one can complement the system by generating a comprehensive database of DUSP-deficient mouse models so that off-target effects of these inhibitors can be easily evaluated, we will be one step closer to seeing the applications of DUSP inhibitors in therapeutic treatments.

Thus, far this review has been restricted to discussion of small intestinal adenoma formation in mouse models, so what of the human CRC? Obviously the cre-lox lineage tracing experiments performed in mice cannot be done in humans, but naturally occurring methylation or mitochondrial mutations can be used to study the fate of stem cells in human samples.

Ppargc1a and Ppargc1b were co-regulated at 6 h PI in the mouse model, so analyses of both the proximal promoter regions and the 3'UTRs of all three PGC family members were performed in silico in order to identify similarities that could account for the observed co-regulation.

Worried that they might be missing important human end points by relying on established inbred strains in research, Threadgill and other scientists created the Complex Traits Consortium (CTC) with a mission, he says, "to reinvent the mouse model so that it would contain genetic variability on the scale of what exists in humans".

But Dr. Pinchas Cohen, chief of pediatric endocrinology at Mattel Children's Hospital at the University of California, Los Angeles, said the mouse models were so complex and hard to understand that their relevance to growth hormone therapy remained "entirely speculative".

Although there is limited genomic information yet, according to mouse models used so far in macular research, these rodents could equally be used to target genes relevant to AMD, i.e. inflammatory, oxidative stress associated, and metabolic pathway genes [32].

These aspects have been only partially elucidated using the Fig4-null mouse models generated so far.

This set of data, therefore, establish PI3Kγ-deficient mice as a mouse model for ADHD with remarkable face and predictive validity, which largely compares to the best genetic mouse models reported so far (Leo & Gainetdinov, 2013).