Sentence examples for mouse models representing from inspiring English sources

To test the potential in vivo significance of the above observations, we investigated the effect of WFA on STS growth, local recurrence, and metastasis using several human STS xenograft mouse models representing different complex karyotype STS histological subtypes.

mRNA and protein expression of the prioritized gene family of metallothioneins was evaluated in postmortem patient brains and in mouse models representing 6 other LSDs.

In conclusion, these mouse models represent valuable experimental paradigms for human pathogenesis.

The approach used in this study to evaluate psoriasis mouse models represents a general strategy that can be applied to score alternative mouse phenotypes with resemblance to specific human diseases.

Mouse models represent powerful tools for gene discovery in human disease.

However, transgenic AD mouse models represent more a familiar form of AD and reflect only partly the entire AD pathology.

Mouse models represent valuable paradigms for studying retinal neurodegenerative and vascular disorders that are analogous in humans.

The use of pre-clinical mouse models represents a common approach exploited to validate laboratory observations in vivo.

Genetically engineered mouse models represent a major advance in cancer research that allows for the study of gene function in vivo and for the creation of models that more accurately recapitulate human cancers.

Jackson Laboratories, for example, claim 'Humanised mouse models represent powerful tools for studying haematopoiesis, inflammatory disease, viral host-pathogen interactions, and are helping to accelerate the development of novel therapies in HIV infection and oncology'.

These mouse models represent an artificial situation in which IGF1 is found in an unbound form and, thus, its post-translational control is impaired and its bioactivity is increased.