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For example, in transgenic hAPP mouse models, relative pathogenic contributions of different hAPP processing products are unknown.
We have identified differences in the extractability of a number of ECM components from the cartilage of MED and PSACH mouse models, relative to controls.
With the advancement of bacterial recombination techniques to engineer reporter gene constructs from BAC genomic clones and the generation of optically distinguishable fluorescent protein reporter genes, there is an unprecedented capability to engineer more informative transgenic reporter mouse models relative to what has been traditionally available.
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To identify the targets of these miRNAs, DNA microarrays were used to examine hepatic mRNA levels in the short-term hypothyroid mouse model relative to controls.
In this study, we described chromosome 3 transcriptome changes for three well characterized EOC cell lines (OV-90, TOV-112D, and TOV-21G) that each responded differently in relation to various growth conditions such as in three dimensional spheroid culture and nude mouse xenograft models, relative to the conventional monolayer culture.
In our mouse model, the relative proportion of multiple cytokine production by CD8 cells was much higher in the i.d.
In the mouse model, the relative amounts of IgG1 and IgG2a (or IgG2c), expressed in the IgG2a/IgG1 ratio, appear to be decisive for protection (40, 56, 57).
However, the profile of aggregate structures that are present in the brains of HD patients or of HD mouse models and the relative contribution of specific aggregate structures to disease pathogenesis is unknown.
When compared with genetic mouse models of HD, the relative larger size of the rat brain is advantageous for application of translational imaging tools, such as positron emission tomography (PET) and magnetic resonance imaging (MRI; von Hörsten et al. 2003; Blockx et al. 2011, 2012).
On the basis of observations in mouse models [ 14, 18], the relative abundance of Firmicutes and Bacteroidetes was associated with the capacity to harvest energy.
CARDS toxin is a likely candidate based on the in vivo effects of rCARDS toxin reported in this study and the fact that the magnitude of CARDS toxin expression by M. pneumoniae is markedly increased in vivo using the mouse model of infection relative to toxin expression during broth culture (T.R. Kannan et al Submitted).
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Justyna Jupowicz-Kozak
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