Sentence examples for mouse models related from inspiring English sources

Here, we briefly discuss a number of knockout mouse models related to GQC and important findings produced from their study.

Studies in different mouse models related to schizophrenia have also described alterations to a variety of intrinsic neuronal properties in the hippocampus.

The role of Cn activity in the pathogenesis of T-ALL was demonstrated in well-designed experiments with the usage of two different mouse models, related to human T leukemias [ 43].

Therefore, although many peripheral symptoms of adult onset HD have been documented, the extent to which the peripheral pathology identified in the mouse models relates to adult onset disease is as yet unknown.

In the phenotype-centric approach, we identified all mouse models and related ortholog genes for the 51 human phenotypes with a comparable phenotype in mice.

We are further investigating this in human blood cells and mouse models by relating this decline in autophagy levels with telomere length.

Furthermore, the mutation of the Dys homolog in the mouse model is related to the up-regulation of the Notch-beta pathway [ 33].

It is not until more relevant humanized xenograft mouse models and phylogenetically related large animal species were used to optimize gene transfer methodologies that unequivocal clinical successes were achieved.

In particular, drugs sharing side effects tend to bind to common protein targets [ 8] and mouse models of functionally related genes often show similar phenotypes [ 9].

However, we should be cautious about preclinical studies in animal models relating to translational research, as immune responses might vary between mice and human systems [80].

As such, a guide to assessing studies in mouse models and salient issues related to translation from mice to humans are included.