Sentence examples for mouse models now from inspiring English sources

The Cancer Genome Atlas (TCGA) analyses and genetically engineered mouse models now provide an integrated approach to dissect these multifaceted and context-dependent driving roles of the TGF-β pathway.

Remarkably, transgenic mouse models now even support the reverse hypothesis, i.e. that tangle deposition is protective, similar to amyloid plaques in amyloid pathology.

Several mouse models now show that cardiomyocyte death itself may directly cause dilated cardiomyopathy.

Several other mutant SOD1 mouse models now exist that also model ALS; these models all have slightly different pathologies, including time to onset of symptoms and death (e.g. Bruijn et al., 1997; Jonsson et al., 2006; Nicholson et al., 2000).

Thus, both conclusions may be correct, and the specific circumstances surrounding a given model and protocol will need to be noted in future studies with the multiple eosinophil-deficient mouse models now currently available.

A recently, developed intravital microscopic mouse model now offers the chance to visualize rolling and adhesive behavior of leukocytes during different stages of fetal development (E13 18) in vivo [29].

"These findings and the mouse model now allow us to figure out the precise neural circuit defects responsible for these abnormal behaviours, which could lead to novel strategies and targets for developing treatment".

Our novel mouse model now provides a useful resource with which to evaluate the impact of aging, as well as various genetic and/or pharmacological modifiers of neurodegenerative disease(s).

Data from the K/BxN mouse model now show that mast cells also have a critical role in the pathogenesis of inflammatory arthritis, in particular in arthritis induced by autoantibody-containing immune complexes.

Mouse models are now available that have human leukocyte antigen (HLA) alleles, and they appear to recapitulate human epitope use.

Mouse models are now available for many ciliopathies, including PCD, ADPKD, ARPKD, hydrocephalus, BBS, Leber's congenital amaurosis, and nephronophthisis (Damerla et al. 2014, Norris and Grimes 2012 ).