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Therefore, the development of mouse models mimicking human immunodeficiency (SCID and OS) allowed us to investigate the pathogenesis of immunological disorders.
We expect MEMRI to be promising for future applications in longitudinal studies on development, aging, or regeneration of CNS projections in mouse models mimicking human CNS pathologies.
In vivo, TRPV4 activation slowed GI motility and reduced stool production in mouse models mimicking pathophysiological conditions.
through epidemiology, genetic and molecular causes, Together with refined tools in pathology, the successful hematological and clinical findings, prognostic factors establishment of mouse models mimicking at least some and current treatment approaches of the diseases.
Multiple kinds of mouse models, mimicking human skeleton diseases caused by missense mutations in FGFs and FGFRs, have been established by knock-in/out and transgenic technologies.
More importantly, it provides the potential to generate unique mouse models mimicking lung interstitial diseases without adversely affecting other organs and systems.
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Shay T, Lederer JA, Benoist C. Genomic responses to inflammation in mouse models mimic humans: we concur, apples to oranges comparisons won't do.
These mouse models mimic many aspects of human tumor development and have enabled informative studies that cannot be performed in patients.
By directly comparing the relative expression ratio of orthologous genes between human and mouse, we assessed how closely the mouse models mimic the gene expression activity of two human HCC subclasses.
The chemically-induced mouse models mimic human sporadic colorectal cancer and are often used to study dietary influences on Carcinogenesis.
Interestingly, these mouse models mimicked the natural progression of del 5q) MDS with approximately a third of mice developing BM failure or AML.
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