Sentence examples for mouse models harboring from inspiring English sources
However, these approaches have only been demonstrated in human tumor-derived cell lines or mouse models harboring mtDNA mutations.
In this review, we provide examples of mouse models harboring modified endogenous gene(s), generated using the technique commonly referred to as the "knock-in" approach, to exemplify the important and sometimes superior role of this methodology in dermatological research.
Mouse models harboring these human mutations were generated but fail to fully recapitulate human AD.
Mouse models harboring both gain and loss of function in Tcf7l2 do not readily reconcile these differences.
The selective vulnerability of motor neurons to degeneration in ALS mouse models harboring mutations in superoxide dismutase (SOD1) has been found to correlate with regional-specific ER stress in brains.
Up regulation of EDC genes as well as changes in other genes are often associated with mouse models harboring skin barrier defects, such as Loricrin, Klf4, and Grhl3 KO mouse models (Segre et al., 1999; Koch et al., 2000; Yu et al., 2006).
A mouse model harboring embryonic deletion of Sav1, Mst1/2 or Lats2 in the heart revealed the importance of these Hippo components for proper organ development [60].
To directly assess the levels of different types of spontaneous mutations in organs and tissues during aging, we have used a mouse model harboring a chromosomally integrated cluster of lacZ-containing plasmids that can be recovered and analyzed in Escherichia coli.
The mouse model harboring leptin V145E mutation will serve as an excellent model for human obesity which results from leptin dysfunction.
The mouse model harboring leptin V145E mutation will provide new information on the current understanding of leptin biology and novel mouse model for the study of human obesity syndrome.
Using a transgenic mouse model harboring chromosomally integrated lacZ mutational target genes, we previously demonstrated that mutations accumulate with age much more rapidly in the small intestine than in the brain.
