Sentence examples for mouse models generated from inspiring English sources

These aspects have been only partially elucidated using the Fig4-null mouse models generated so far.

Several transgenic mouse models generated to understand the molecular mechanisms of AD also reproduce loss of dendrites and spines.

Many aspects of the molecular pathophysiology of FRDA remain to be addressed using the different mouse models generated.

Mouse models generated via engraftment of primary human tumors into immune-compromised mouse models have become increasingly popular for preclinical testing of anticancer drugs.

Most BRCA1 mouse models generated to date have deleted Brca1-Iris in addition to full-length Brca1 (Evers and Jonkers, 2006).

Further, we compared our expression results against the databases of the ABA, BGEM, and EGFP-reporter mouse models generated throughout GENSAT.

Very few of these mouse models generate spontaneous tumours, however, and tumours may differ histologically and genetically from human medulloblastomas.

APP transgenic mouse models generate N-truncated Aβ peptides, albeit at quite low levels not reflecting the situation in AD brain.

In order to study the disease pathology of PSACH in a more physiologically relevant model, we report the generation and phenotypic description of the first knock-in mouse model generated by homologous recombination and harboring the common D469del COMP mutation.

To this end, we employed a viable SGK1 knockout mouse model generated in a 129/SvJ background.

Design: Using a mouse model generated on a C57BL/6 background (wild type, WT) in which the GOAT gene has been deleted (KO), we measured plasma AG, UAG and GH concentrations and tissue (stomach, pituitary and hypothalamus) preproghrelin and GOAT mRNA in non-pregnant (NP) and pregnant (P), WT and KO mice.