Sentence examples for mouse models further from inspiring English sources

Familial Hemiplegic Migraine 1 (FHM1) and 2 (FHmutationsionsharere the ability to facilitate the induction and propagation of CSD in mouse models, further supporting the role of CSD as a key migraine trigger [13].

Recent functional analyses of genetically engineered mouse models further suggest that EPAC1 functions as an important stress response switch and is involved in pathophysiological conditions of cardiac stresses, chronic pain, cancer and infectious diseases.

Analysis of two mouse models further supported the idea that CpdA has potent anti-inflammatory activity but exerts only little side effects when applied in vivo.

Altogether, the extensive regulation of our gene signature at different developmental stages and in differentiating cortical neurons, as well as in several neurological mouse models further supports their importance for the proper functioning and development of the mouse brain.

The general agreement between these results and observations made on individuals with DS, as well as on mouse models, further support the validity of the Tc1 mouse as a model for DS.

Adenovirus-mediated silencing of CHD1L could inhibit HCC tumorigenesis in xenograft mouse model further suggested CHD1L as a potential therapeutic target in HCC treatment (Chen et al., 2011).

In order to improve sustainability of parasitemia in the mouse model further, we investigated immunosuppressive agents that might help to minimize the innate immune response.

APP overexpression has been employed in fly models of AD [25], [26]; moreover, altered circadian patterns of activity have been reported in the APP23 mouse model, further strengthening this possibility [27].

Although our results appear consistent with the mouse model, further studies are needed to understand how COMT behaves differently in the maternal and fetal compartments to modulate the risk for preeclampsia.

The finding that Aβ4-x precedes AβpE3-x in the well accepted 5XFAD AD mouse model further underlines the significance of Aβ4-x.

11, 12, 16 In fact, data from the Zfyve26−/− mouse model further support a role for the endolysosomal system in SPG15 pathogenesis.