Sentence examples for mouse models figures from inspiring English sources

We took advantage of the multiple optical imaging techniques and evaluated the target specificity of fluorescently labeled POH by using HIF-specific bioluminescence imaging in cancer mouse models (Figures 2, 3, 4, 6).

This allowed us to identify 49 upregulated and 111 downregulated probes (corresponding to 40 and 88 genes), which represent to a novel candidate gene set associated with development of full leukaemia in these two AML mouse models (Figures S3, S4 and Table S2 in Supporting Information S1).

The potential usefulness of DT385 as an antitumor agent was evaluated in both the chick CAM assay (Figure 6) and the Lewis lung carcinoma mouse model (Figure 7).

Construction of FAM20LU resulted in both OpaON and OpaOFF clones, which showed no differences in growth, in adhesion and invasion of host pharyngeal epithelial cells, or in virulence using the CD46 transgenic mouse model (Figure S1 and data not shown).

To determine the applicability of EXB Plus not only in human but also in other organisms, we used tumors from two different xenograft-mouse models (A431- and H1975-xenograft) and extracted proteins from three different mice for each mouse model (Figure 3).

We found that loss of Rb did not change the number of mice that do not develop HCC within one year, suggesting that Rb deletion does not affect cancer initiation and confirming that tumorigenesis is driven by activation of MYC in this mouse model (Figure 6A).

In summary, the changes in gene expression profile observed in the XpdTTD liver are consistent with increased cellular and metabolic responses to genotoxic stress, which can explain most, if not all, of the premature aging phenotypes in this mutant mouse model (Figure 4).

Furthermore, we also demonstrate evidence for a synergistic effect of the combination of an entry inhibitor with a DAA in vivo using the human liver-chimeric uPA/SCID mouse model (figure 9).

(for the principal structure of PNs in the used mouse models see Figures 1b e).

Hematoxylin and eosin staining of tumour sections clearly showed PanINs as well as areas with well-developed tumours compared with the control pancreas from contemporary littermates of both KC: K-rasG12D; Pdx1-Cre (40th and 50th weeks) and KPC: K-rasG12D; Trp53R172H/+; Pdx1-Cre (5th, 10th, 15th, 20th and 25th weeks) mouse models (Supplementary Figures 1a and b).

We therefore identified sets of genes associated with such in vitro KC responses to cytokine treatment and evaluated how these gene sets were altered in both psoriatic skin from humans and lesional skin from mouse model phenotypes (Figure 10).