Sentence examples for mouse models employed from inspiring English sources

(B) Box plots showing the COV ratios grouped according to the 11 mouse models employed.

It is conceivable that the amount of prelamin A in the GMF-TG mice might be less than that found in the mouse models employed for secondary laminopathies.

Moreover, FcγRIIa may be inhibited in the above-described mouse models employing specific FcγRIIa blockers [ 50– 50].

Studies in mouse models employing adoptively transferred lymphocytes have emphasised a key role of the upregulation of CCR5 in TILs in mediating tumour rejection (Gonzalez-Martin et al, 2012).

However, tumors were grown up to at least 6-mm diameter (≈100 μl) before the start of the treatments, and evident signs of necrosis were seen on PET images during follow-up and, in some cases, even at day 0. A more recent investigation using spontaneously occurring mammary STAT1 −/− tumors in a mouse model employed FDG and steroid receptor PET imaging to follow up hormone therapies [26].

The type II GD mouse model employed in this study was generated by Enquist et al.

Therefore the injection of non-dissociated tumorspheres, in combination with the immune-deficient mouse model employed (NUDE mouse strain), contributed to the high tumor engraftment rates observed.

Another consideration is that loss of CFP expression in the Thy1-CFP mouse model employed in the present study may differ from the loss of RGC function [ 26].

It would also be interesting to extend this analysis to other tumours in mice models employing inhibitors of other components of the PI3K pathway, such as Akt, PDK1, S6K1 and SGK isoforms, that are becoming available.

We perused publicly available data (NHGRI database for human associations and Mouse Genome Informatics database for mouse models) and employed two alternative approaches for cross-species comparisons, phenotype- and gene-centric.

Preclinical mouse models have employed targeting of a single tumour antigen with some success.