Sentence examples for mouse models compared from inspiring English sources

The edited AZIN1 showed strong oncogenic phenotypes on HCC cell lines and mouse models, compared with the wild type form.

This discrepancy is difficult to interpret, though may relate to the relative small size of tumours in mouse models compared to patients, where diffusion of the radiotracer may potentially overcome poor delivery by destroyed vasculature.

H2O2 increased the activity of both α1 and α2 AMPK in addition to Akt phosphorylation, and H2O2-stimulated glucose uptake was not reduced in any of the AMPK transgenic mouse models compared with wild type.

Increased protein levels for Timp1, Lcn2, Igfbp2, Pfn1, and Sparc were observed in ovarian tumor tissues isolated from K-ras/Pten (Figure 3A) and Pten/Apc (Figure 3B) ovarian cancer mouse models compared to control tissue lysates.

We also demonstrate that methylation of the PPARγ2 promoter was increased in visceral adipose tissues of obese diabetic mouse models compared to that observed in wild-type mice.

Of note, age-dependent impairment of oxygen consumption, such as a decrease of state 3 and of uncoupled respiration, was observed in several APP transgenic mouse models compared to aged-matched controls [ 5, 14, 43, 47].

Genotype and sex dependent differences in longevity have important implications for designing experiments with Alzheimer's mouse models, comparing genotype and sex differences in aging mouse models, designing drug treatment regimes and the translation of mouse data to human clinical studies.

Thus, in mouse models comparing only XXY gonadal males with XY gonadal males, it is difficult to separate organizational hormone effects from the direct effects of sex chromosomes on non-gonadal tissues.

Serum acetaldehyde levels are relatively and significantly high an ALDH2*2 mouse model compared with control mice even under non-alcohol drinking conditions23, suggesting that ALDH2 functions in pathways other than alcohol metabolism.

Marker gene expression showed that the reversibly shielded polyplexes exhibited up to 2 log orders of magnitude higher gene expression in vitro and 1 log magnitude higher gene expression in an in vivo mouse model, compared to the stably shielded control polyplexes.

The first model as described previously is the cerebella of KIKO mouse model compared with WT control.