Sentence examples for mouse models based from inspiring English sources
Conditional mouse models based on the Cre-recombinase (Cre -loxP method are a powerful tool for determining the spatial and temporal funCre -loxPgenes in neuroscience research.
Consequently, we referred to established mouse models based on known influenza virus strains.
Our project represents a systematic comparison of GWAS-derived associations in humans and corresponding information from mouse models, based on curated and publicly available data.
To study the genome-wide dynamics of leukaemogenic transcriptional reprogramming, we used two established transplantable AML mouse models based on retroviral transduction of normal bone-marrow progenitor cells with MLL-ENL or MOZ-TIF2 fusion proteins, respectively.
So far, humanized mouse models based on the transplantation of human HSC only – i.e. without additional human tissues – share these limitations, and immunization strategies result in the limited generation of class-switched antigen-specific B cell responses [14], [31], [32].
The absence of full-blown neurofibrillary changes, i.e. argyrophilic neurites, neurofibrillary tangles or neuropil threads, is in line with other transgenic mouse models based on the (co- expression of APP and presenilin mutants whico- expressioneurofibrillAPP pandology.
To gain mechanistic insights, we developed a novel mouse model based on a mutation in human optineurin associated with hereditary, low-pressure POAG.
Some of the insertion mutants were analyzed for virulence in the mouse model based on intradermal (ID) administration of graded doses of bacteria.
In summary, we developed a new EH mouse model based on the use of a subcutaneous E2 sustained releasing pellet.
Recently, an MM mouse model based on intracisternal infection of adult mice with group C N. meningitidis has been developed [ 30].
Different dosimetry models were tested ranging from spheres with just self-doses with activity inside the tumour or organ, to a cylindrical mouse model [ 4] with cross-organ dose contributions, to a realistic mouse model based on ultrasound imaging geometry.
