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Discover LudwigThe phrase "mouse modeling" is correct and usable in written English
It can be used in contexts related to scientific research, particularly in biology or medicine, where mouse models are used to study diseases or test treatments.
Example: "In our study, we utilized mouse modeling to investigate the effects of the new drug on tumor growth."
Alternatives: "murine modeling" or "mouse-based modeling"
Exact(19)
In the RCAS/Tv-a glioma mouse modeling system, avian retroviruses (produced from RCAS plasmids) infect mouse cells expressing Tv-a (the receptor for RCAS viruses).
A previously published study demonstrated the usefulness of progeroid models, in particular the Zmpste24-null mouse modeling Hutchinson-Guilford Progeria Syndrome, in identifying miRNAs regulating organismal aging.
Brigitte Widemann (National Cancer Institute) described previous human trials for plexiform neurofibroma, utilizing agents such as farnesyl-transferase inhibitors, antifibrotic drugs, and immunomodulary agents (interferon) that have been completed with mixed and somewhat disappointing results; these trials were based on some preclinical testing, but not detailed pre-clinical mouse modeling.
To provide maximal experimental utility and enable the translation of preclinical mouse modeling experiments into human disease, GEMMs of human CRC must be driven by homologous allelic series, and exhibit similar clinical presentations to the human disease, including disease histopathology and appearance of metastatic lesions (Heyer et al., 2010; Roper and Hung, 2012).
Mouse modeling of mtDNA transmission and disease has recently taken advantage of cybrid approaches.
It also addresses the versatility of mouse modeling using newly developed techniques recreating human protocols and sophisticated genetically engineered approaches that aim to characterize the biology of gliomagenesis.
Similar(39)
There are now mouse models of Parkinson's.
"Blocking tumor necrosis factor in a mouse model improves asthma," Dr. Remick said.
The problem is there are no appropriate mouse models that can mimic the human situation.
"We had the virus, the mouse model, and two vaccines to test".
Like Li, he employs mouse models to expand understanding of our own bodies.
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