By using the DSS-induced colitis mouse model, we demonstrated that miR-223 deficiency resulted in more severe symptoms.
The mouse model we developed is quite reliable but has a steep learning curve, so a technician has been key.
Using a human tumor xenograft mouse model, we next demonstrate that AuNP-loaded T cells retain their capacity to migrate to tumor sites in vivo.
In our pursuit to establish such a mouse model, we designed a dual inducible Cre transgene system and tested it in cultured cells.
In the Snord116 deletion mouse model, we observed normal locomotor activity and excellent wire-hanging ability.
Using this new mouse model, we identified self-reactive thymocytes with an immature CD4loCD8lo phenotype.
Using a mouse model we documented deleterious effects of advancing paternal age on offspring behavior.
Using our chronic Salmonella-infected mouse model, we further observed the Salmonella burden in various organs over 27 weeks.
To study type 2 diabetes in a mouse model we chose the leptin receptor knock out mouse model (Leprdb).
Using a mouse model, we showed that intraperitoneal injection of OMVs derived from intestinal Escherichia coli induced lethality.
In an in vivo LCMV mouse model, we repeatedly detected an increase in CD4+ effector cells in Cdc42−/− mice.
