Sentence examples for mouse model utilizing from inspiring English sources

Kim et al report their findings with a mouse model utilizing ovalbumin and Aspergillus protease to induce eosinophilic inflammation.

The study assessed the histological effects of perineural injections of propylene glycol and three medical gels in a mouse model utilizing ultrasound guided microinjection techniques.

As an alternative, a mouse model utilizing repeated doses of bleomycin has been proposed to more closely replicate pathological features of IPF in humans (Degryse et al., 2010).

In these studies, we generated a mouse model utilizing the Cre- loxP system to ablate CENP-F protein expression in a cardiomyocyte-specific manner (termed CENP-F −/− hereafter).

Besides the ability to detect and identify diseased state, the profile demonstrates the potential to monitor tumor response to chemotherapy in an orthotopic mouse model utilizing this miRNA profile.

These cellular defects are not strictly dependent on the individual hypomorphic MCM allele used, as a mouse model utilizing an MCM2IRES-CreERT2/IRES-CreERT2 allele, which resulted in a reduction in total protein level to roughly 1/3 the wild type amount, exhibited similar defects in dormant origin usage and genome instability [45,62].

Collectively, these three studies ([26], [27], and the data we report here) confirm that the SOD2 allele impacts upon AD-like pathology, but clearly the effects vary according to the AD mouse model utilized.

The JNPL3 mouse model utilizes the mouse prion promoter [ 5] to drive mutant human tau expression [ 31].

Transgenic mouse models utilizing constitutively active or dominant negative MEK have also been very useful in delineating the roles of MEKs in development and disease.

In contrary to GEMMs, carcinogen-induced mouse models utilizing either chemical compounds or hormones are less time-consuming and less cost-intensive 11, 12. Hormone-induced models may actually be more representative of the condition observed in human patients regarding the mechanism and disease progression of EH.

Notwithstanding differences in the mouse models utilized (Mecp2tm1Tam [24], Mecp21lox [25] or Mecp2tm1.1Bird [this report]), the enrichment paradigms (continuous from 4 weeks of age [24], continuous from 3 weeks of age [25] or transient from 3 to 5 weeks of age [this report]) and the methods used to test its effects, EE is capable of eliciting improvement in some RTT like phenotypes.