Sentence examples for mouse model suitable from inspiring English sources

Until now, a mouse model suitable for studying the genetics of the inherited predisposition to renal tumor has not been described but, as we show here, does already exist.

Given the well-established importance of menstrual cycle activity as a risk modulator for breast and extra-uterine Müllerian carcinomas, our intention was to generate a mouse model suitable to investigate the interplay between genetic and hormonal factors of predisposition to both of these cancers.

In mice, CRP levels do not respond to inflammatory stimuli, making mouse models suitable for studying cardiovascular effects of SAA without interference of CRP effects.

Mouse models suitable for replicating the early, non-proliferative stages of the retinopathy have been characterized, but no animal model has yet been found to demonstrate all of the vascular and neural complications that are associated with the advanced, proliferative stages of DR that occur in humans.

Ratios of PiB in APP/PS1 transgenic mice closely resembled the ratios measured in our cohort of AD patients, further supporting the notion that our transgenic mouse model is suitable for PET imaging studies of Aβ pathology.

The results indicate that the proposed ER+/ERαKD tumor-bearing mouse model is suitable to test pure antiestrogen and aromatase inhibitor therapies in vivo in a preclinical setting and could help to elucidate the impact of ERα levels on tumor response to hormone therapy.

Thus, binding of Fg to M5 inhibits complement deposition in the mouse system, confirming that the mouse model is suitable for studies of Fg-binding to M5.

Both phenomena resemble the situation in humans and therefore make the oocyte mouse model a suitable one for studying individual variations to chemotherapy as well as deciphering the role of aging.

Therefore, in a major extent, mouse model is suitable for studying human FXR functions.

The presented mouse model is suitable for investigating the mechanisms of allergic eczema.

Overall, our goal is to better model human DCIS, in a reproducible and robust mouse model system suitable for interventional studies.