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Previous studies of NDV-vectored vaccines in a mouse model suggested their potency after delivery by injection or by the intranasal route.
Results from the mouse model suggested that the transcriptional activity of buffy coat-isolated cells may be used to monitor the onset of and recovery from acute infection.
The lack of triglyceride accumulation in our hypothyroid mouse model suggested that hypothyroidism caused by MMI may not cause the steatosis in NAFLD.
In this study, the miRNA profile of the ventricles of a transgenic HCM double mutant mouse model suggested downregulation of miR-1 and miR-133 in a primary stage of the disease prior to a pathophysiological change [ 40].
The observed redistribution of p54nrb/NONO protein in cell culture and in a transgenic mouse model suggested that this protein could be sequestered into pathological aggregates in human FUSopathies.
Our electrophysiology and behavior results, combined with the phenotypic similarities between the AS mouse model and the haplo-insufficiency Reelin mouse model, suggested to us that we examine the endogenous Reelin protein profile in the cortex and hippocampus of the AS mouse.
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We also show that the QKCMP can bind to excised tissues from burn injuries in cutaneous mouse model, suggesting its potential for promoting neovascularization of burn wounds.
Furthermore, even in the less well epigenetically defined case of fibromyalgia, mS-11 ameliorated symptoms in a mouse model, suggesting that fibromyalgia is related to the dysfunction of NRS F/REST
Importantly, in vivo studies showed that this synergism was able to generate significantly increased new bone in an ectopic mouse model, suggesting that PCL/HA-3D scaffolds act as a favorable synthetic extracellular matrix for bone regeneration.
However, the inhibitory activity of the anti-deltac mAb in the chimeric mouse model suggests that additional gamma cutilizing cytokines regulate the development of the remaining subsets of IEL.
The minor defects observed in our mouse model suggest a mild effect from ATRX deficiency that may manifest only occasionally.
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