Sentence examples for mouse model such from inspiring English sources

Inbred BALB/c mouse strain was employed because it is more receptive to lung gene delivery when compared to other mouse model, such as the SCID mouse [ 17].

This limitation in knowledge must be considered in making decisions to move to clinical trials based on drug responses observed in a partial trisomy HSA21 mouse model, such as the Ts65Dn.

The gold standard for functional validation is to generate a mouse model such as a transgenic, or knockout and look for a perturbation of phenotype such as incubation time.

Beyond that, anle138b represents a novel compound that significantly attenuates all features of human tauopathies recapitulated in the PS19 mouse model, such as cognitive decline, neuropathology, and accelerated mortality [ 11, 50].

The coexpression network analysis underscores the main biological processes affected by alcohol and miRNA regulation in the mouse model, such as synaptic vesicle-mediated transport and endocytic recycling, as well as neuroimmune signaling mediated by chemokine and Toll-like receptor signaling.

While we agree with reviewer 1 that it would potentially be useful to perform passive transfer experiments with IgG3 antibodies in the IgG3-deficient MRL/ lpr mouse model, such experiments are not guaranteed to recreate the in vivo conditions that obtain during the evolution of spontaneous glomerulonephritis.

For this purpose, the use of OSCC mouse models, such as chemically induced mouse models, genetically modified mouse models, and transplanted (xenograft) models, is crucial.

Physiological and pathological changes were examined using islets from various mouse models such as non-obese diabetic (NOD), ob/ob, db/db mice and during pregnancy.

Substantial progress has been made in cell therapy strategies and in gene- and cytokine-introduced angiogenesis using a variety of mouse models, such as hind limb ischemia models.

Finally, we discuss emerging mouse models, such as second-generation pathophysiology models based on innovative approaches that are facilitated by the information gathered from the current genetic mouse models.

Gender-related phenotypic differences have been found in other long-lived mouse models such as the Ames dwarf mouse which shows a greater lifespan increase in females [13].