Sentence examples for mouse model significantly from inspiring English sources

Overexpression of PDGF-D in a mouse model significantly enhanced prostate carcinoma onset and invasiveness [ 184].

The gapmer also decreases r(CUG 960 expression in a DM1 mouse model, significantly improving other DM1-associated defects.

More recently, Taes et al. reported that the deletion of HDAC6 in an ALS mouse model significantly extends survival and maintains motor axon integrity without affecting disease onset.

Intravenous injection of these lipoplexes into a HBV mouse model significantly reduced viral protein expression during at least 8 days in only a single treatment.

Systemic delivery of miR- 506 in an orthotopic ovarian cancer mouse model significantly augmented the cisplatin response, thus recapitulating the clinical observation.

Finally, elevation of plasma PROG to a mean concentration of 5870 pg/ml in an Ala315Thr (A315TARDBPDBP transgenic mouse model significantly reduced the rate of loss of locomotor control in PROG-treated, compared with placebo, mice.

The intravenous administration of TfR-lytic peptide in the athymic mice model significantly inhibited tumor progression.

Furthermore, the intravenously administration of TfR-lytic peptide in the athymic mice model significantly inhibited tumor progression.

The local intratumoral administration of [D]-K3H3L9 in the athymic and syngeneic mice models significantly inhibited tumor progression.

In an in vivo orthotopic NB mouse model, P22077 significantly inhibited the xenograft growth of three NB cell lines.

Experimentally the ability of the A549 lung cancer cell line to form lung metastases in a mouse model is significantly reduced upon stable expression of LIMD1 [4].