Sentence examples for mouse model showing from inspiring English sources
The resultant strain, MTBVAC erp−, was tested in severe combined immunodeficiency (SCID) mouse model showing to be severely attenuated when compared to BCG and MTBVAC.
Differences in blood clearance rates were observed between the murine and human FcRn mouse model, showing that one alanine mutation in the Fc-huFcRn binding site (i.e. I253A, H310A or H435A) was sufficient to completely abrogate binding to huFcRn and generate hu3S193 antibodies with clearance rates as fast as hu3S193 antibody fragments (e.g. (Fab′ 2) without an Fc fragment.
These findings were supported by a sepsis mouse model showing that caspase-12 mice had a higher bacterial count and lower pro-inflammatory cytokine production during sepsis [11].
To our knowledge, this is the first report of a mouse model showing metastasis both through hematogenous and lymphatic route.
This hypothesis is reinforced by a transgenic mouse model showing spontaneously reduced eating alongside robust circadian rhythms and increased life span.
This is consistent with findings for the SOD1G93A mouse model showing that these mice have high iron levels and that iron chelators extend their life span [ 34].
Further characterization of the RIPK1 KO mouse model showed that the deletion of RIPK1 led to bone marrow aplasia and loss of hematopoietic stem and progenitor cells (HSPCs 16.
In addition, MRI and photothermal effect for mouse model showed enhanced T1 signal and temperature elevation in tumor site with photoirradiation.
In vivo implantation of the LZ scaffolds in a mouse model showed absence of foreign body reaction to the scaffold.
Immunoprecipitation of Akt in pre-symptomatic mSOD1G93A muscle and end-stage atrophic muscle from this mouse model showed binding of CTMP to Akt (Fig. 1E), corresponding to the increased expression of these proteins over time.
Initial characterization of this mouse model showed that under baseline, no-stress conditions, increasing adult neurogenesis enhances pattern separation, but has no effect on anxiety or depression-related behavior (Sahay et al, 2011).
