In addition, MRI and photothermal effect for mouse model showed enhanced T1 signal and temperature elevation in tumor site with photoirradiation.
In vivo implantation of the LZ scaffolds in a mouse model showed absence of foreign body reaction to the scaffold.
In vivo efficacy tests in a mouse model showed compounds 66 and 72 to be promising candidates as they exhibited significant parasitemia reductions of 96.4% and 80.4%, respectively.
Analysis of one of these mutants in a psoriasis mouse model showed its efficacy in promoting the recovery of psoriasis plaques.
Depletion of the NCKX3 gene in a KO mouse model showed loss of bone mineral contents and increased plasma parathyroid hormone, suggesting that NCKX3 may play a role in regulating calcium homeostasis.
Subcutaneous implantation of the cell/scaffold constructs in a nude mouse model showed that the scaffolds favorably supported survival of the grafted cells and their commitment to the three desired lineages in vivo.
Recent studies in the mouse model showed that telomerase might have a fundamental role in tumour growth and survival [8].
The 3xTg-AD mouse model showed memory impairment at an early age because of Aβ accumulation in neuronal cells [8], [9].
Previous studies with the Tgfbr2fspKO mouse model showed that the conditional stromal knockout of TGF-β signaling led to CRPC [5].
Previous studies from our laboratory, demonstrated that proliferating mammary epithelial cells in a conditional Chk1 heterozygous mouse model showed miscoordinated cell cycle events and spontaneous DNA damage foci formation [10].
A recent study using an engineered mouse model showed the importance of intact signaling via the PI3K RAS-effector arm for initiation of lung tumors in a RAS-mutant mouse [14].
