Sentence examples for mouse model provided from inspiring English sources
We demonstrated that a single intranasal, but not intramuscular, vaccination with AdAg85A in a mouse model provided a level of protection against pulmonary M.tb challenge that was comparable to or even better than that by standard s.c BCG vaccination [10].
The human SKOV-3 cell xenograft mouse model provided the opportunity to evaluate species differences in the effort to classify cancer-associated proteome as either tumor-derived (human) vs. host response (mouse).
The molecular cloning of seven v-rDNAs (Tseng et al., 2007, submitted) and the construction of the basonuclin-null mouse model provided us with the first opportunity to test the notion that a transcription factor could regulate a subset of rDNA.
Studies with the Scurfy (sf) mutant mouse model provided the required breakthrough.
Accordingly, the mouse model provided L-fucose, enabling B. thetaiotaomicron to synthesize L-fucose containing polysaccharides.
Assays for inflammatory cytokines in the mouse model provided additional concordant evidence that by the time the recovered SCV fraction was highest, acute inflammatory markers had returned to pre-infection control levels.
The humanized mouse model provides an alternative model to study in vivo human biological response.
In summary, this mouse model provides important insights into CLC development and suggests inhibition of phosphatidylinositol 3-kinase (PI3K) signaling as a potential therapeutic strategy for targeting CLC.
Although 10-fold greater quantities of antibody are required to observe significant effects in mouse, compared to our previous studies in rats, the present mouse model provides a convenient paradigm for investigating catalytic and non-catalytic antibodies.
Altogether, the proposed ER+/ERαKD tumor-bearing mouse model provides a promising preclinical platform to investigate novel ER-specific therapies using PET imaging.
Small-molecule drugs that help to fold and process proteins correct type 2 diabetes in a mouse model, providing a new lead for the treatment of human diabetes.
