Sentence examples for mouse model proposed from inspiring English sources
On this basis, in order to understand if PML restrains tumourigenesis by regulating mTORC1, we utilized a tumour mouse model proposed to depend on aberrant activation of mTOR, but not Akt.
Strong evidence from mouse models proposes that altered expression of SAC proteins leads to aneuploidy that can initiate and promote tumourigenesis, and cause tumour relapse after chemotherapy (Dobles et al, 2000; Sotillo et al, 2007; Weaver et al, 2007; Sotillo et al, 2010).
In summary, our data argue against the mutually exclusive model proposed for mouse primitive erythrocytes [5] [7].
Current IS animal models either focus on a specific cause of IS, such as the loss of interneurons (i.e., the ARX mouse model), or propose a final common pathway underlying all causes of IS [ 26].
Results from the analysis of a real example in mouse have validated the usefulness and utilization of the model proposed.
A direct comparison of candidate vaccines in well-characterized mouse models was proposed.
The rasH2 transgenic mouse model has been proposed to evaluate the carcinogenic potential of medical devices, but few data are currently available regarding study design – namely appropriate positive and negative controls to be used – as well as historical pathology data.
The rasH2 transgenic mouse model has been proposed to evaluate the carcinogenic potential of medical devices, but very few data are currently available regarding study design-namely appropriate positive and negative controls to be used-, as well as pathology historical data.
Collectively, our results indicated that GO-induced immune responses down-regulated Th2-facilitated IgE production and lung eosinophilia in a mouse model of asthma, proposing a novel mechanism of nanoparticle-induced airway remodeling and AHR in asthma.
An imiquimod-induced dermatitis mouse model has also been proposed to reproduce psoriasis-like skin changes (van der Fits et al., 2009).
