Sentence examples for mouse model progresses from inspiring English sources

The HD phenotype in the YAC128 mouse model progresses slowly and corresponds relatively well to the human condition.

With a novel orthotopic mouse model, progress has been made in identifying a breast cancer stem or initiating population from TN breast cancer patients [ 54].

A human population-based cohort with graded severity of existing cognitive impairment and a mouse model with progressing neurodegeneration both indicate that the risk of delirium increases with greater severity of pre-existing cognitive impairment and neuropathology.

In a recent report using a PTEN- and TP53-null prostate adenocarcinoma mice model that progresses via TGF-β-induced EMT, SNAIL2 was the main driver of EMT activation.

This suggests that the metabolic demand increases in the tissues of this mouse model as the disease progresses.

In summary, the current data support the concept that inhaled CO is capable of reducing inflammation to a moderate degree in a mouse model of relatively slowly progressing pulmonary inflammation/barrier dysfunction induced by a low dose of intratracheal LPS.

In a very aggressively progressing tau mouse model (Tg4510) that shows extremely rapid tau aggregation and neuronal loss, it was shown that the tau aggregates impair ER proteostasis, thus contributing to activation of the UPR [ 1].

Translocation of cytochrome c from the mitochondria to cytosol was also seen in a mouse model of HD as the disease progresses.

Thus, we have established and validated a novel application to noninvasively measure AAA development and progress in a mouse model using a high-frequency US imaging system that has the advantages of low cost, rapid imaging speed, reproducibility and high resolution, and makes repeated monitoring of the progress of AAA development over a time-course possible.

We recently started working on a mouse model for malaria in which we follow the progress of a Plasmodium chabaudi infection.

Gastrin over-expressed in an insulin-gastrin transgenic mouse model (INSGAS) induces corpus atrophy in those mice, spontaneously progressing to gastric adenocarcinoma with advanced age [31], [32].