Sentence examples for mouse model mice from inspiring English sources
The combined use of the in vivo boost study in CYP3A4-humanized mouse model mice along with PBPK modeling accurately predicted the clinical outcome and identified a significant NVS123 exposure boost (∼42-fold increase) with ritonavir.
c Biodistribution of [131I]-I2-PARPi [131I]-I2-PARPi [131I]-I2-PARPidel (mine were sacrificed 2 h after tracer injection, additional biodistribU251n data can be found in Additional file 1: Tables S3A and S3B).
In the mouse model, mice vaccinated with recombinant AHSV VP7 have also shown very variable anti-VP7 antibody responses.
For DIO mouse model, mice were randomly grouped with free access to one of the three experimental diets (n = 15/group) containing 10 kcal% (LFD), 45 kcal% (HFD) and 60 kcal% (VHFD) fat, respectively (Research Diets).
In this mouse model, mice invariably succumb to a CML-like disease in about 3 weeks.
In a cancer-resistant mouse model, mice constitutively expressing the TERT had longer telomeres and extended lifespan [ 149].
This idea derives from studies using progeroid mouse models (mice with accelerated physiological aging due to genetic disorders), where elimination of senescent cells delayed the presentation of age-related disorders55.
In mouse models, mice with specific defects in folate transport had higher rates of neural tube defects after in utero arsenic exposure than wild-type mice similarly exposed [ 5, 11].
RESULTS: To explore Glis3's role in adults, we generated two independent mouse models: mice with haploinsufficiency of Glis3 (Glis3+/−) and inducible pancreatic beta cell-specific Glis3 deficiency (Glis3 fl/fl /Pdx1Cre ERT+ ).
We also found that WNK4 D561A/+ knock-in mice, model mice of human PHAII patient, caused phenotypes similar to those of PHAII (Yang et al. 2007).
For the GBM mice model, mice were observed daily following tumor cell injection; 10 days after xenograft transplantation, the healthy mice were randomized to radiation treatment group of 12 mice each.
