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These studies with a mouse model indicate that PAF-AH is not a major secondary target of OP pesticide poisoning.
Open wound healing tests with a mouse model indicate that the catechol-chitosan film suppresses the bacterial population at the wound site, induces less inflammation and promotes wound healing.
Our findings showing up-regulation of CCL20 and SLPI in B. pseudomallei-infected in vitro cultured cells and in vivo mouse model indicate an epithelial-initiated anti-microbial response against B. pseudomallei.
Detailed studies of pathological events in the mouse model indicate that changes associated with disease become measurable within 3 days of challenge with C. albicans, including body weight, systolic blood pressure, blood glucose, urea, chloride and creatinine levels [9].
These observations gathered in the Mdr2−/− mouse model indicate that MTA could be useful for the treatment of biliary fibrosis and conditions such as primary sclerosing cholangitis, a severe disease frequently associated with hepatobiliary cancer and with limited therapeutic options.
However, the results in this mouse model indicate that even with correct use, N9 may fail to protect against vaginal HSV infections.
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Similarly, in vivo evaluations in KP mouse model indicated successful CD44/EGFR-targeted delivery.
Preclinical assessment of p52−/p36− GAP in a humanized mouse model indicated an early and severe liver stage growth defect.
In conclusion, the mouse model indicated retarded disease progression upon cessation or switching to pMRTP which alone had no adverse effects.
Collectively, we demonstrated that miR-17~92 miR-17~92d tumor progresuppressednhibitumortumor angiogenesis in a genetically engineered mouse model, indicating the progression cellular context-dependent pro- and anti-cancer effects of miR-17~92.
The efficacy of nintedanib at improving lung function has also been shown in a recent IPF mouse model, indicating that it not only reduces fibrosis but also significantly enhances the pulmonary microvasculature [15].
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CEO of Professional Science Editing for Scientists @ prosciediting.com