Sentence examples for mouse model experience from inspiring English sources

Similar to other mouse models of prostate cancer, tumors from our PTEN-deficient mouse model experience an initial response to ADT that is followed by the eventual development of CRPC (4, 5, 37, 38, 39).

They attributed the discrepancy between the mouse model and the clinical experience to the physical properties of human zona pellucida, specifically its bilayered organization and concluded that zona thinning was not clinically beneficial.

The importance of CD14 for a pro-inflammatory response in heart tissue was emphasized in a mouse model, where CD14-deficient mice experienced no ventricular dysfunction and decreased cytokine mRNA expression after LPS challenge [ 21].

Our experience in transgenic mouse model preparation has led to the conclusion that having an alternative method is highly favourable.

Some data exist to support this mechanism since pre-existing antibodies have been shown to enhance infection in monocytes in the immunocompromised mouse model and human monocytes can also experience enhanced infection ex vivo when exposed to DENV in the presence of heterologous post-immune serum (Halstead et al., 1973; Shresta et al., 2006).

Sample sizes for the mouse work were decided based on previous experience in a related mouse model (Rafiqi et al, 2010).

Since these pathological changes and lymphoma development were not expected in our vast experience with estrogen-treated mouse model, we excluded these two estrogen-lymphoma mice in the main body of study.

The choice of a mouse model rather than human tissues was based on experience from numerous studies that have highlighted the challenges associated with the use of archival human tissues, both from technical and biological viewpoints [16].

The prednisolone dose was chosen based on our extensive pre-clinical experience with this drug in the mdx mouse model.

Here we investigated the relationship between a genetic predisposition to trait anxiety and experience-based learned fear in a psychopathological mouse model.

In addition to the clinical experience linking anti-ARS antibodies with lung pathology, a mouse model of anti-Jo-1 immune response demonstrates predominant lung disease [ 21].