Sentence examples for mouse model during from inspiring English sources

The current study utilizes [18F]FAZA to detect functional changes in the microenvironment of a renal cell carcinoma mouse model during sunitinib therapy and subsequent withdrawal.

Betatrophin is mainly expressed in the liver and fat and its plasma level is associated with β-cell proliferation in insulin resistance mice and the mouse model during gestation.

However, to the best of our knowledge, there is no information regarding which particular tryptase is expressed in the mouse bladder and/or upregulated in this mouse model during inflammation.

Notably, it has been demonstrated that Bim is upregulated in a familial ALS (fALS) mouse model during the symptomatic stage and ablation of BIM in vivo reduced cellular apoptosis in the ventral horn of a transgenic mouse model of fALS, increasing lifespan.

However, it seems that only two of the four cysteines significantly contributed to SOD1 aggregation by this crosslinking in mouse models during the disease process (5, 6).

81, 82 The microbiome composition changes in mouse models during the development of obesity, and fecal transplantation transfers an obese phenotype to wild type recipients.

The generation of dozens of tau transgenic mouse models during the past years (reviewed in [ 34, 35]) has facilitated studying the potential role of tau in neurodegenerative diseases (reviewed in [ 2, 15]).

Since the mechanisms underlying the development of sporadic AD are still uncertain, this study has significant implications for the analysis of distinct AD transgenic mouse models during preclinical drug evaluation for treatment of early-stage AD.

The increased concentration of potassium in the perilymph surrounding free lateral surfaces of outer hair cells (OHCs) creates a toxic microenvironment, contributing to progressive hair cell (HC) loss in both of these mouse models during the late postnatal period when the EP and hearing are being established in the mouse (21, 22).

We aimed to characterize features of microvascular function during MetS development in a mouse model, particularly during the initial phase when confounding factors known to influence microvascular function are not completely established.

We next found in our mouse model that during thymic involution, nuclear particles in the cytoplasm of the macrophages, apoptotic thymic cells, and IgG deposition to the thymic cells were all increased, particularly in the cortex (Fig. 4).