Sentence examples for mouse model displayed from inspiring English sources
As shown in Fig. 7(a+b d+e), the control groups of both, athymic and immunocompetent mouse model, displayed exponential tumor growth throughout the three-week therapy.
It reduces the incidence of metastases in orthotopic mouse model, displayed anti-invasive activity, and inhibited angiogenesis.
Accordingly an IRS1 knock-out mouse model displayed a MetS like phenotype with insulin resistance, increased blood pressure, increased triglycerides, decreased HDL cholesterol and decreased LPL activity [ 35].
In the case of MK5, the KO mouse model, displayed either no particular phenotype or embryonic lethality, depending on which genetic background the mice were bred [ 6, 7].
By analysing tendon formation in absence of muscle using a genetic mouse model displaying loss of branchiomeric muscles, we were able to demonstrate that tendons initiate their development independently of muscles but that muscle is required for further tendon development.
Mutations in the human FOXP3 gene causes the disease Immune dysregulation, Polyendocrinopathy, Enteropathy, X-linked syndrome (IPEX) [5], and the Foxp3 mutant Scurfy mouse model displays a similar pathology involving dysregulated CD4+ T cell infiltration and activation [6] [8].
Smn 2B/−mice, an intermediate SMA mouse model, display fasting hyperglycemia and glucose resistance at a young age (28).
This mouse model displays several phenotypes that recapitulate aspects of the human condition and provides mechanistic insight into the disease.
This well-characterized mouse model displays the identified neuropathological hallmarks of human tauopathies, pathological behavioral phenotypes, and increased mortality [ 11, 50].
The KTA048 mutant line is the first mouse model displaying similar eye phenotypes as found in human patients carrying PXDN mutations.
The THY-Tau22 mouse model displays a broad timely resolution of tau pathology with hyperphosphorylation of tau at younger age (up to 6 months) and abnormal tau phosphorylation and tau aggregation in aged mice (by 10 months).
