Sentence examples for mouse model demonstrating from inspiring English sources
The only inducible mouse model demonstrating axial ankylosis as well as a strong immune component is the proteoglycan (PG -induced sPG -inducedmodel (PGIspondylitis
He described successful chemoprevention studies in the C3(1) Tag mouse model, demonstrating that both dihydroepiandrosterone and 2- difluoromethyl -dl-ornithine are effective chemopreventative agents.
Importantly, these results are corroborated using the E2F1 knockout mouse model, demonstrating that the TGF β E2F1 signaling pathway mediates TGF β-induced cell death not only in a diseased state but in a normal cell setting as well.
HGF also cooperates with Shh to induce tumor formation, and the inhibition of HGF with a monoclonal antibody was able to increase survival in this mouse model demonstrating the potential for HGF-targeted therapies [49].
The immunosuppressive activity was confirmed in vivo, using a delayed-type hypersensitivity autoimmune mouse model, demonstrating a significant reduction of symptoms of disease compared with the control group [45].
Another study by Wang et al. [ 10] reported in vivo photoacoustic micro-imaging of microvascular changes for Achilles tendon injury on a mouse model, demonstrating that photoacoustic imaging can potentially be a complementary tool for high sensitive diagnosis and assessment of treatment performance in tendinopathy.
Results of anti-diabetic assay using C57BL/KsJ-db/db mouse model demonstrated that compound 9 was effective at lowering blood glucose, total cholesterol and HbA1c (P < 0.01).
Additionally, studies in the DMD mdx mouse model demonstrate that cellular uptake of a PMO is enhanced by co-administration of a glucose-fructose formulation, resulting in the restoration of higher dystrophin protein levels in the skeletal muscle [97].
The BFS-1 mouse model demonstrated a tendency (p<0.09) for tumor weight reduction after treatment with the peptide (Fig. 7 (f)).
The inducible character of our HGF mouse model demonstrates that prenatal development is the specific stage influenced by activation of Met signalling.
Histopathologically, the mouse model demonstrated accumulation of abnormal lysosomal inclusions in multiple tissues and neuronal cell loss with concomitant astrocyte activation [18], [19].
