Sentence examples for mouse model demonstrate from inspiring English sources

Integration of human genetics, patient metabolite and cytokine measurements, and testing in a mouse model demonstrate that the methionine salvage pathway is a regulator of sepsis that can accurately predict prognosis in patients.

Additionally, studies in the DMD mdx mouse model demonstrate that cellular uptake of a PMO is enhanced by co-administration of a glucose-fructose formulation, resulting in the restoration of higher dystrophin protein levels in the skeletal muscle [97].

Virulence studies in the mouse model demonstrate that, like IUM 96-2828, the strain is significantly less virulent than H99.

Vaillant and colleagues, using breast primary tumor xenografts in a nonobese diabetic/severe combined immunodeficient (IL2Rγc−/−) mouse model, demonstrate that the combination of tamoxifen and ABT-737 or ABT-199 produced the largest reduction of tumor volumes and much longer survival outcome than tamoxifen or ABT drug alone.

Intrauterine inoculation with ZIKV in a mouse model demonstrated that ZIKV infection of the placenta increases production of IFNβ, which, in turn, stimulates ISG expression to limit viral infection.

Furthermore, pharmacological stabilisation with DMOG was also found to be protective in a colitis mouse model, demonstrating an anti-apoptotic phenotype in intestinal epithelial cells that the authors suggested maintained the epithelial barrier44.

Earlier studies using the same mouse model demonstrated long-term pulmonary engraftment of cord blood- or iPSC-derived macrophages, whereas no cells could be detected in other organs associated with homing of macrophages28,29.

Results of anti-diabetic assay using C57BL/KsJ-db/db mouse model demonstrated that compound 9 was effective at lowering blood glucose, total cholesterol and HbA1c (P < 0.01).

The BFS-1 mouse model demonstrated a tendency (p<0.09) for tumor weight reduction after treatment with the peptide (Fig. 7 (f)).

The inducible character of our HGF mouse model demonstrates that prenatal development is the specific stage influenced by activation of Met signalling.

Histopathologically, the mouse model demonstrated accumulation of abnormal lysosomal inclusions in multiple tissues and neuronal cell loss with concomitant astrocyte activation [18], [19].