Sentence examples for mouse model collectively from inspiring English sources

Although further research is required to dissect the underlying mechanisms and evaluate the potency of AFMC and TRAIL co-treatment in a nude mouse model, collectively, these results raise the possibility that combined treatment with TRAIL and AFMC could be a promising candidate therapeutic for human lung cancer.

Collectively, these mouse model studies clearly show a prooncogenic role for NOTCH1 in lung adenocarcinoma development within a KRAS-mutated cellular context.

Collectively, these findings suggest that our mouse model provides an important experimental platform for probing the underlying mechanisms responsible for this unique disease.

Collectively, these results demonstrate that the rtTA/MIC mouse model can be used to study Cre recombinase-dependent genetic alterations in conjunction with PyV mT oncogenic activation.

Our results collectively demonstrate that the p23-ST1 mouse is a novel mouse model of human NPH.

Collectively, supported by two human xenograft models and a spontaneous mouse model, our work clearly indicated that Ponatinib significantly prevents and inhibits breast cancer metastasis to the lungs in mouse models.

Collectively, these data demonstrate that the osteolytic bone microenvironment in our mouse model mimics the bone microenvironment in human breast cancer but not that of other metastatic microenvironments (i.e., lung and brain metastases).

The BALB/c isogenic series of mammary tumour lines collectively known as 'the 4T1 model' has been the principal transplantable mouse model used to study both tumour- and host-derived factors involved in spontaneous metastasis (Aslakson and Miller, 1992; Eckhardt et al., 2005; Kusuma et al., 2012).

We show that these properties collectively reduce the risk of organ infections and vertical transmission in a mouse model but remain sufficiently immunogenic to prevent wild-type ZIKV infection.

Collectively, we demonstrated that miR-17~92 miR-17~92d tumor progresuppressednhibitumortumor angiogenesis in a genetically engineered mouse model, indicating the progression cellular context-dependent pro- and anti-cancer effects of miR-17~92.

Collectively, for the first time, we demonstrate that parasitic infection inhibits AD-like skin lesions in a mouse model of AD.