Sentence examples for mouse model based from inspiring English sources
To gain mechanistic insights, we developed a novel mouse model based on a mutation in human optineurin associated with hereditary, low-pressure POAG.
Some of the insertion mutants were analyzed for virulence in the mouse model based on intradermal (ID) administration of graded doses of bacteria.
In summary, we developed a new EH mouse model based on the use of a subcutaneous E2 sustained releasing pellet.
Recently, an MM mouse model based on intracisternal infection of adult mice with group C N. meningitidis has been developed [ 30].
In our study, we used CXCR4 inhibitors as single agent and choose to use the xenotransplantation mouse model based on the NOG immunodeficient mice transplanted with primary patient cells.
More recently, the case for miR-15a/16-1 deletion having a causative role in CLL was strengthened with the generation of a CLL mouse model based on knockout of this locus [ 29].
Conditional mouse models based on the Cre-recombinase (Cre -loxP method are a powerful tool for determining the spatial and temporal funCre -loxPgenes in neuroscience research.
Consequently, we referred to established mouse models based on known influenza virus strains.
Our project represents a systematic comparison of GWAS-derived associations in humans and corresponding information from mouse models, based on curated and publicly available data.
To study the genome-wide dynamics of leukaemogenic transcriptional reprogramming, we used two established transplantable AML mouse models based on retroviral transduction of normal bone-marrow progenitor cells with MLL-ENL or MOZ-TIF2 fusion proteins, respectively.
The absence of full-blown neurofibrillary changes, i.e. argyrophilic neurites, neurofibrillary tangles or neuropil threads, is in line with other transgenic mouse models based on the (co- expression of APP and presenilin mutants whico- expressioneurofibrillAPP pandology.
