However, also less destructive variants of IAV are able to induce lethal synergism in a mouse model [10] arguing for additional mechanisms.
Use the "Pros and Cons" model; argue for a position, and then argue against it.
Indeed, it had been demonstrated that proteasome activity is correlated with mitochondrial malfunction and oxidative stress in a mouse model of neurometabolic disease, arguing for a role of mitochondria dysfunction in ROS-mediated proteasome activation.
Thus, our combined analysis of the mouse model and the human samples argues for COX activity as a common mechanism co-opted by cancer cells to promote immune escape across species.
In conclusion, our findings argue against LSCs, or other nonhepatocyte cell types, providing a backup system for hepatocyte regeneration in this common mouse model of chronic liver injury.
M.P.C. and L.B.S. generated humanized mouse model.
A mouse model of familial hypertrophic cardiomyopathy.
Taube, S. et al. A mouse model for human norovirus.
(A) The KA mouse model of chronic epilepsy.
