Sentence examples for mouse miRNA expression from inspiring English sources

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Using customized RAKE miRNA microchips [23], we profiled wild-type mouse miRNA expression in developing cerebellum at postnatal stages P7 and P60 (Table 1 and Figure S1).

All human and mouse miRNA expression values were normalised to RNU6B and SnoRNA202, respectively.

Recent analysis of human and mouse miRNA expression profiles, however, has shown that the relative expression levels of the two strands vary widely among tissues [ 19].

MECP2 expression levels were normalized to GAPDH, human miRNA expression levels to RNU43, and mouse miRNA expression levels to sno-142.

The multi-tissue mouse miRNA expression data were from a mammalian miRNA expression altas based on small RNA library sequencing [ 8].

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Likewise, in retinas of newborn mice (P0), miRNA expression was mainly detected in the vitreal cell layer of the retina (i.e. INBL) where differentiated ganglion and amacrine cells reside (see blue arrowheads in Figure 4A, first column).

In the current study, we systemically investigated the development and function of LCs during aging using C57BL/6J mice and performed miRNA expression profiles of LCs between aged and young mice.

Sera of cancer-positive and -negative mice exhibited higher miRNA expression similarity (R=0.971) than pairs of tissue and serum samples in the two groups of mice (P<0.001 for both; Student's t-test), indicating that only some miRNAs overexpressed in cancer tissues could be released into the serum.

To evaluate a potential role for DNA methylation in the control of miR-200c/141 in mice, CpG methylation and miRNA expression were analyzed in mouse epithelial cells (epidermis of SKH-1 mouse and keratinocyte cell lines 308 and 6R90) and mouse fibroblasts (cell lines NIH 3T3, NIH 3T6, and NR6).

Although a functional role for miRNAs during SLE has not yet been demonstrated by using mouse models, alterations in miRNA expression levels in PBMCs and kidney biopsies from patients with SLE have been described [ 41, 42].

Therefore the primary aims of this study were to (1) identify BAT-enriched miRNAs by comparing miRNA expression mouse BAT, skeletal muscle and WAT using PCR-based miRNA arrays (2); predict the BAT-enriched miRNA target genes potentially involved in growth, proliferation and development; (3) compare the miRNA profiles of mouse and human BAT.

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