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The dose-dependent relationship of endotoxin on food intake and fecal output was investigated by determining the time courses for each endpoint after administration of 0.005, 0.01, 0.02, 0.04, 0.1, 0.2, and 0.4 mg/kg mouse mass of endotoxin.
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In the sham-operated mice, mass of food intake was significantly decreased in mice on the high fat diet compared to the chow-fed mice (Fig. 1C).
In the colon of 12-week-old MMP9 −/−:Plg −/− mice, mass lesions of various dimensions were detected.
As there is no ELISA available for mouse PLTP, mass of plasma PLTP could only be measured in the huPLTPtg/wt→LDLR−/− and huPLTPtg/tg→LDLR−/− mice.
We used previously published data on relative activity concentration of 131I and 211At in thyroid in mice [26], an absorbed fraction of 0.742 and 1 for radiation emitted from 131I and 211At, respectively [27], and a standard mouse thyroid mass of 3 mg.
2. Determine weight of the mice and calculate mass of streptozotocin (Sigma S0130) needed for injections of 100 ml per mouse.
In our previous study [ 17] we have shown that at 16 weeks of age, despite being more insulin resistant than ob/ob mice, the β-cell mass of POKO mice remained similar to that of WT islets.
38 mice with tumor mass of about 1 gm were injected in the tail vein with 100 µCi of 99mTc-labeled mAb to galectin-3 (30 µg protein/in 100 µl saline solution).
In contrast, in female mice, the masses of both TA and soleus muscle were not significantly affected by the absence of nNOS (Figure 1B and 1C, respectively).
Although CF mice are pancreatic sufficient, in contrast to most CF patients, CF mice are about 70% the mass of WT mice from before weaning into early adulthood [ 27].
Investigation of early mouse embryos confirmed that the differentiation of the inner cell mass of mouse blastocysts to trophoblast derivatives and extra-embryonic endoderm parallels the induction and accumulation of K8 and K18 [4]–[6].
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