Sentence examples for mouse macrophages we from inspiring English sources

Unlike the LPS-induced response in THP-1 cells and mouse macrophages, we failed to observe up-regulation of miRNA-146 or -155 [ 38, 39].

Using stable isotope labelled mouse macrophages, we have recently isolated phagosomes derived from the internalization of IgG-opsonized latex beads from a sucrose density gradient.

To generate mouse macrophages, we differentiated bone-marrow cells isolated from wild-type C57BL/6 mice and from B6.B10ScN- Tlr4 lps-del mice (Jackson Laboratory) according to standard procedures [ 26].

With mouse macrophages, we found that α1m, α2m, and Gc-globulin, at concentrations similar to those measured in synovial fluid [ 33- 35], each dose-dependently stimulated the production of TNF, whereas AGP 1, albumin, and haptoglobin did not.

In contrast to a previous Nlrp1c expression screen in mouse macrophages, we did not observe expression of this paralog in macrophages of mice belonging to the groups defined by Boyden and Dietrich as allelic groups 3 (AKR/J and NOD/LtJ), 4 (DBA/J), and 5 (CAST/EiJ) [ 17].

Coupled to the translational data with human NASH, and a series of mechanistic readouts in human and mouse macrophage, we unveil an AnxA1-centerd pathway engaged by the host for liver protection.

To confirm the expression of FcγRI on the surface of mouse alveolar macrophages, we tested the binding of FcγRI-specific antibodies on the surface of alveolar macrophages isolated from the BALF of wild-type and FcγRI−/− mice by flow cytometry.

It is known that human, rabbit and mouse antibodies can support the uptake of particles by mouse macrophages [35]; however, we tested species matched antibodies to confirm the effect of IgM on phagocytosis.

To investigate a potential role of NF-κB in PL-induced CCL20 and IL-23 expression, we pretreated mouse macrophages with an inhibitor of NF-κB (acetyl-11-keto-b-boswellic acid [AKBA]) before stimulation with PL.

Finally, confocal microscopy of in vitro tissue culture experiments in which we challenged mouse macrophages with Pa ATCC43949 revealed that bacteria were either internalised or invaded macrophages rapidly but were then capable of re-emerging from the cells by growing in a filamentous form.

Based on microarray data obtained from primary mouse macrophages cultured with IL-4, we found that the expression of 103 lysosomal genes was dependent on Stat6, reflecting 40% of the known lysosomal proteome and 54% of lysosomal genes expressed in this cell type; 45 of these genes have been associated with human diseases [ 89].