Sentence examples for mouse lupus this from inspiring English sources

In mouse lupus, this evidence included decreased numbers of Foxp3+ Tregs in the early stage.

An example among may: In a mouse lupus nephritis model, aggregated immunoglobulins react with fibronectin physicochemically; this reaction in turn causes clustering of integrins and internalization of immunoglobulins by glomerular endothelial cells, resulting in fine in glomerular injury [44].

*This region is orthologous to that containing the mouse lupus susceptibility locus sle7 [107].

There is, however, an important difference that distinguishes human lupus from mouse lupus.

In this study, we identified miRNAs differentially regulated in peripheral lymphocytes in the mouse lupus model B6.Sle123.

Fas lpr mouse model is mainly derived from extrafollicular responses, which is not the case for all mouse lupus strains.

In the MRL.Fas lpr) mouse lupus model, B cell-derived IL-10 does not regulate spontaneous autoimmunity [ 89].

High IL-18 and/or IL-12 production is observed in glomeruli of human and mouse lupus nephritis.

Conversely, the AD transfer was possible in normal mice after allograft from a mouse lupus nephritis showing that it was in fact a stem cell disorder.

In vivo and in vitro silencing of miR-21 using small, seed targeting LNA inhibitors de-represses PDCD4, a protein involved in cell proliferation and apoptosis and ameliorates cardinal SLE manifestations in mouse lupus.

Indeed, recent electron microscopic co-localization experiments in human and mouse lupus kidneys indicated that antibodies present in the glomerulus are bound to electron-dense deposits that were identified to be nucleosomal material [ 15].