Sentence examples for mouse liver transcriptome from inspiring English sources

Akhtar, R. A. et al. Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus.

Mouse liver transcriptome data was obtained from mice administered different diets and the number of measurements in each group was five.

Results show extensive age-related changes in every component of the mouse liver transcriptome and a pronounced increase in inter-individual variation.

Protocols and data are available through ArrayExpress under the accession E-MEXP-1195 E-MEXP-1195 E-MEXP-1195me on AffymetRat), E-MEXP-889 (Rat liver transcriptome on Affymetrix), E-TABM-500 (Rat kidney transcriptome on Operon), E-TAffymetrixat kidney transcriptome on Illumina), E-MEXP-8895 (C57BL/6J mouse liver transcriptome on Affymetrix).

It is also relevant that the effects human diets have on mouse liver transcriptomes can be used as a model for expression differences between humans and chimpanzees [ 79].

To obtain a genome-wide catalog of genes in mammalian metabolic tissues that are potentially nuclearly retained, we extracted nuclear and cytoplasmic fractions from MIN6 pancreatic beta cell line (Miyazaki et al., 1990) and mouse liver and performed whole-transcriptome RNA sequencing (RNA-seq).

Here, we utilized an RNA-sequencing approach capable of capturing the whole transcriptome of mouse liver, a similar approach that has been performed in aging brain for other mammals [ 14, 15].

We have used a drastic approach, that is the knockout of the miRNA biogenesis factor Dicer (Harfe et al., 2005), to assess how the rhythmic transcriptome in mouse liver is altered in the absence of miRNA-mediated regulation.

To assess differences across species and tissues, we simulated from the mouse liver, mouse brain and maize transcriptomes.

These findings indicate that the liver transcriptome from aged mice is consistently more variable than that from young mice and that this increased inter-individual variation is attributable, in part, to the stochastic variation observed at the level of specific transcript types.

To directly analyze the global transcriptome of aging mouse liver, we isolated total RNA from three young adult (4 months) and three old (28 months) male mouse livers and performed directional whole transcriptome sequencing [ 16].