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Only one CRG, rev-erba, showed 24-hour variation in fetal rat liver (E20) [42], consistent with the lack of rhythms in E18-19 fetal mouse liver reported here.
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Recently, Denzler and colleagues analyzed the stoichiometric relationship of miR-122 and target sites in adult mouse liver and reported that the natural abundance of target sites exceeded miRNAs, making the ceRNA hypothesis unlikely (Denzler et al., 2014).
Using nanotechnology and CRISPR, Prof. Daniel Anderson has turned off a cholesterol-related gene in mouse liver cells, reports Julie Steenhuysen for Reuters.
Recently, the crystal structure of aldehyde oxidase of mouse liver has been reported.
A different laboratory that had established a distinct breeding colony reported mouse liver tumor incidences in 12 PPAR-α null Sv129/C57BL/6 mice aPPAR-α nully 2 yearSv129/C57BL/6royd et al. 2004).
The FACS-based isolation of primary HSC from mouse livers has been reported from several groups [ 12– 18] with considerable variations in the exact gating strategy.
Deacetylation and activation of SIRT3 target proteins within mouse liver mitochondria have also been reported in response to the metabolic stress induced by acute fasting/refeeding and obesity (ob/ob mice), which seems to correlate with higher oxidative metabolism (68).
It has been reported, in mouse liver, that PXR is retained in the cytoplasm in a complex formed by hsp90 and the co-chaperone CCRP, and in presence of ligand, PXR is accumulated in the nucleus [ 24].
Using the female mouse liver gene expression data, we report edge scores for the known causal relationships Insig1 → Dhcr7 and Insig1 → Fdft1 and the other edges depicted in Figure 4.
c-Myc was reported to induce mouse liver tumors with elevated glucose and glutamine catabolism (Yuneva et al., 2012).
PEG10 is not only involved in embryonic development but PEG10-induced expression was also reported for regenerating mouse liver [15].
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