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Our results show that clock gene expression in mouse liver is also locked to lights off.
Another relevant monomeric nuclear receptor where data from mouse liver is available is for the Reverb-α transcriptional regulator [ 24].
Collectively, these findings suggest that the potential for rhythmic miRNA activity in mouse liver is relatively low.
This data indicate that the p.S466L protein that is present in mouse liver is enzymatically active, forms tetramers, but lacks AdoMet inducibility.
In particular, we assumed in this analysis that ChIP-seq binding of TFs in the mouse liver is highly representative of binding of those TFs in other tissues.
However, although the consequences of PPARα activation in the mouse liver is relatively well defined (Mandard et al. 2004), the consequences of human PPARα activation in response to TRI and other peroxisome proliferators is still poorly understood.
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The histology changes of mouse liver was assessed by hematoxylin and eosin staining.
Oxidative stress and antioxidant status in mouse liver were also analysed.
To study the spatial and temporal distribution of lipid species and their abundances, a shotgun lipidomics study of isolated nuclei and mitochondria of mouse liver was performed.
Although increased mRNA levels for UCPs in mouse liver were detected during sepsis, so far there is no unequivocal evidence that they are linked to mitochondrial uncoupling under such conditions [82].
The efficacy of this same vector for expression of AAT in vivo in the nondividing cells of mouse liver was determined by hydrodynamic injection of naked plasmid DNA by means of the tail vein.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com