Sentence examples for mouse lines of from inspiring English sources

In 2007, two different genetically engineered mouse lines of mutations in the GNE gene were described, harbouring either M712T [47] or D176V [48] mutation.

We have recently generated novel mouse lines of cholinergic deficiency by targeting the vesicular acetylcholine transporter (VAChT knockdown - VAChT KD and VAChT knockout - VAChT del/del).

Where tissue availability was limited, the mouse lines of choice were RIII and tg338.

Note that each round of homogenization included at least one representative from each of the two mouse lines of the three genotypes.

Notably, however, the magnitudes of the vocalization differences in S321X heterozygotes were small, and even larger differences could be observed between the wild-types of the two mouse lines of our study.

Generation of knockout mouse line of the Slc39a13 gene was performed using previously described methods [75].

The knockout mouse line of the Slc39a14 gene was generated using previously described methods [60].

We have generated a Sertoli cell-specific knockout mouse line of Cyp26b1 by crossing floxed Cyp26b1 (Cyp26b1fl/fl) animals with mice expressing Cre recombinase under the control of the anti-Müllerian hormone (Amh) promoter.

Samples of the small and large bowel (n = 3 of each mouse line) of about 1 mm3 were rapidly collected and fixed in cold buffered Karnovsky's solution/2% glutardialdehyde/2% paraformaldehyde (pH 7.4) for 2 h.

A mouse line of mutated gp130 in which the SHP-2/SOCS3-binding site was disrupted developed a RA-like joint disease with increased production of Th1-type cytokines and immunoglobulins of the IgG2a and IgG2b classes [ 78].

In this regard, it is noteworthy that the 'NIH' FXTAS mouse line of Usdin and co-workers (26, 68, 69), which does not produce RAN products, exhibits a neurodegenerative phenotype, whereas the 'Dutch' FXTAS mouse line, which is capable of generating RAN products, does not have a significant neurodegenerative phenotype (2).