We discovered that this allele has actually been inadvertently backcrossed into multiple mutant mouse lines, including two engineered to be deficient in Siae and Cmah.
Several knock out mouse lines including H2-K b−/− D b−/−, β2M −/−; TAP1 −/−, β2M −/−, CD3ζ −/−, C1q −/−, C3 −/− show disrupted eye-specific segregation with similar phenotype (Huh et al., 2000; Datwani et al., 2009).
Potential mechanisms that might be involved in bringing about the described alterations in the circadian GC rhythm of our mouse lines include variations in the activity of neural networks (assessable as brain glucose metabolism differences across times of day) as well as abnormal levels or patterns of noradrenalin and melatonin secretion [6] [8], [12].
This locus is linked to increased dystrophic cardiac calcinosis in numerous mouse lines including the D2, compared to mice lacking the Dyscalc gene locus [ 12].
Delays in the establishment of spermatogenesis have been discovered in several mouse lines, including the POG insertional mutation (FancL knockout) mouse line (Lu and Bishop, 2003), using a comparative histology approach.
Neurological deficits were not unique to one particular strain of mouse, as we observed this behavior in five different mouse lines including wild type C57BL/6, wild type BALB/c, 129S1/SvImJ, 129S6- Slc11a1tMcgMcg, and B6.129- Inpp5dtm1 Rkh.
Neurological deficits were not unique to one particular strain of mouse, as we observed this behaviour in five distinct mouse lines including wild type C57BL/6, wild type BALB/c, 129S1/SvImJ, 129S6- Slc11a1tMcgMcg, and B6.129- Inpp5dtm1 Rkh.
Five mouse lines including C57BL/6, Balb/c, 129S6- Slc11a1tMcgMcg, 129S1/SvImJ, B6.129- Inpp5dtm1 Rkh were used in the murine typhoid model to examine the dissemination of systemic Salmonella enterica serovar Typhimurium following oral infection.
SjS-like disease in our NOD-derived mouse lines, including C57BL/6.NOD- Aec1Aec2, is characterized generally by three criteria [ 4], reflecting the objective criteria used to identify SjS in humans [ 25].
To study unperturbed locomotion patterns, locomotion adaptation when crossing obstacles, interlimb coordination as well as cognitive parameters of motivation and avoidance, we subjected four different cell type-specific mutant mouse lines including Pcd, L7-Pp2b mice, L7-Δγ2 mice and α6-Cacna1a mice to the Erasmus Ladder task.
