Sentence examples for mouse lines generated from inspiring English sources
In the three mouse lines generated we could not evidence defects in early skeleton formation.
It is a common observation that mouse lines generated with the same transgene construct can differ in their expression and show a mosaic pattern.
In conclusion, we find unexpectedly that MMTV-Cre line A, one of the three widely used MMTV-Cre transgenic mouse lines generated by the Hennighausen laboratory, exhibits a severe lactation defect.
In addition, we uncovered that the MMTV-Cre transgene is physically linked to the K14-agouit transgene in all of these MMTV-Cre mouse lines generated by the Hennighausen laboratory [5], [6].
Thus, although it was possible in the study to obtain specific and high quality mRNA from fluorescent cells, this approach only rarely will be applicable since in most transgenic mouse lines generated so far the cytosolic form of the fluorescent protein has been used.
In particular, the C57BL/6NTac and 129P2 substrains were specifically chosen in this study because we felt that they would be useful baselines for mouse lines generated in extensive genetargeting studies.
The Cdc42loxP/loxP Fgfr3-iCre-ERT2 Cdc42loxP/loxP Fgfr3-iCre-ERT2 Cdc42loxP/loxP Fgfr3-iCre-ERT2nowledge the first in vivo mouse modelineth impaired scar formation followingeneratedto the organ of Cortin
In this report, we describe a mutant mouse line generated by viral insertion that disrupted the C-terminal deacetylase domain while preserving the N-terminal domain.
Similar results were obtained for a second Muc16 lacZ mutant mouse line generated from an independently targeted ES cell clone (data not shown).
For that purpose we used a Cx57-deficient mouse line, generated in a C57BL/6 background, and compared it to wild-type C57BL/6 mice, in which horizontal cell coupling was unperturbed (Fig. 1).
The reduced viability and blood phenotype (described later) of this S1PL−/− gene-trap line was recapitulated in another S1PL knockout mouse line generated by homologous recombination in which exons 7 8 were replaced by a cre-lox selection cassette (data not shown).
