Sentence examples for mouse lines for from inspiring English sources

It may also be that screening inbred mouse lines for a preponderance of monomeric TRAP could identify the genetic origin of the allele.

The Krt12rtTA/tet-O-Cre system has been previously used to generate mouse lines for inducible gene ablation in a corneal epithelium-specific manner [29].

Newly generated mouse lines for each rtTA variant subtype, rtTA2-M2 and rTA2-nM2, have been cataloged as rTA-M2CaMK-2, rTA-nM2CaMK-4 rTA-nM2CaMK-6 rTA-nM2CaMK-7 and rTA-nM2CaMK-8.

This was also suggested in other BSE transmission studies in RIII or C57Bl mouse lines, for which quite a wide range of mean incubation times has also been reported (range 393 909 days in BSE transmissions to C57Bl mice) [24].

Limitations to the clinical relevance of the HR/IR/LR mouse lines for instance include that HPA axis dysregulation is currently not one of the critical diagnostic criteria for MD and that it is a genetic model, i.e. the differences in stress responsiveness are already present early in life, thereby potentially influencing developmental processes that shape the respective endophenotypes.

Large-scale projects are working at generating transgenic mouse lines for all genes, which can be used in confirmatory studies.

Homozygous mice with OGR1 floxed (OGR1fl/fl ) were bred to germ line Cre mice Zp-3 (a transgenic mouse line for the inactivation of loxP-flanked target genes specifically in the female germ line [26]; Jackson Labs, Bar Harbor, Maine).

In addition, they were bred to Prm (Protamine-Cre, a transgenic mouse line for the inactivation of loxP-flanked target genes specifically in the male germ line of mice [27]; kindly supplied by Dr. Guangbin Luo, Case Western Reserve University) to generate OGR1+/−Cre mice, which were bred further to generate OGR1−/− (KO or deficient) mice.

We previously made a Tgfb3-Cre mouse line for palatal epithelium studies [23], and we also found that the Tgfb3 promoter-driven Cre induces recombination in the suprabasal layer of the epidermis and hair follicle epithelium including the bulge region (Figure 1).

We recognize that our comparison between PTGDS and HPGDS is based on only one transgenic mouse line for each mutant.

Mice from the TauP301L responder line were crossed with mice from the BAC-LRRK2 mouse line for one generation to obtain LRRK2.TauP301L responder mice on an FVB background.