Sentence examples for mouse lines containing from inspiring English sources

Three independent mouse lines containing this construct were utilized in this study.

Chimeric males derived by injecting ES cells into blastocysts were used to establish mouse lines containing the desired point mutations as well as the floxed NeoR cassette used for ES cell selection.

To capitalize on the separable nature of FP reporters we have generated transgenic mouse lines containing different FP spectral variants allowing us to cross two or more mouse lines together to further define bone cell populations [ 6].

By crossing a mouse line containing floxed alleles for Dicer, a critical protein for the generation of mature miRNAs, with a Rx-cre transgenic mouse line, we conditionally deleted Dicer in all the cells of the retina and ventral hypothalamus from the initiation of their development.

However, despite this limitation, when the sEGFP7 mouse line containing a Cre-activated enhanced green fluorescent protein (EGFP) was infected with the Cre expressing virus, sites of latent and persistent virus infection could be identified within B cells and macrophages of the lymphoid system on the basis of EGFP expression.

Ms4Yah mice were obtained through in vivo chromosomal engineering using a mouse line containing loxP sites in a cis configuration and the Prmt2 and Cstb loci crossed with a general CRE deleter strain, Tg(CMVCRE) 1pcn.

We turned to commercially available transgenic mouse tools to determine if we could use a mouse line containing a GFAP promoter to drive expression in peripheral non-myelinating Schwann cells.

TgS100a8a9 hep mice were generated by breeding of the hepatocyte-specific transactivator (tTA) mouse line TALap1 with the TetOa8a9 transgenic mouse line, containing the Myc/His-tagged S100a8 (tgS100a8) and S100a9 (tgS100a9) transgenes under the control of a tTA-dependent and bidirectional promoter.

Briefly, we used a knock-in mouse line containing CAG-loxP-STOP-loxP-rabies-G-IRES-TVA at the Rosa26 locus (RΦGT) (Takatoh et al., 2013) crossed with a mouse line that expresses Cre recombinase under the control of the choline acetyltransferase (ChAT) gene (Chat::Cre mouse, JAX Stock #006410).

Crossing these mice with a mouse line containing floxed alleles of the particular gene of interest has provided us with the means to examine the role of any gene in just about any tissue or cell type for a role in bone biology.

Saturation mutagenesis could effectively be performed in these regions by generating a transgenic NOD mouse line containing a transposon concatemer near the region of interest and taking advantage of the propensity of SB transposons to reintegrate close to the donor transposon concatemer (Keng et al. 2005).